Ways to Increase Your Body’s NAD+ Levels

girl with high NAD+ Levels

NAD+ is a vital molecule in the human body that supports numerous metabolic functions, particularly those related to energy production, DNA repair, and cell health. However, due to various lifestyle factors, NAD+ levels naturally decline with age, leading to decreased vitality and increased risk of chronic diseases. 

This blog explores effective tips to enhance your body’s NAD+ levels and promote overall well-being.

What is NAD+?

NAD+ is a coenzyme found in all living cells and is vital for energy production, DNA repair, and cellular health. It is crucial in converting cellular energy and regulating pivotal cellular processes, including metabolism and aging.

NAD+ coenzyme

What Causes Decreases in NAD+?

While NAD+ levels naturally decline with age, certain lifestyle factors can accelerate this decrease, impacting overall health and vitality.  Several factors contribute to the depletion of NAD+ in the body, which can affect health and accelerate aging processes:

  • DNA Damage: Exposure to environmental stressors like UV radiation and toxins can damage DNA, requiring NAD+ for repair. Frequent DNA repair depletes NAD+ more quickly.
  • Alcohol Use: Regular alcohol consumption can dramatically decrease NAD+ levels as the body uses up its NAD+ stores to metabolize alcohol, reducing the availability of other cellular processes.
  • Overeating: Consuming excessive calories requires more NAD+ for energy production, which can deplete NAD+ reserves over time.
  • High Blood Sugar and Insulin Levels: Increased blood sugar and insulin due to poor diet or conditions like diabetes can lead to NAD+ depletion, as more of this coenzyme is used to help manage and process glucose levels in the blood.

How To Increase NAD+ Levels?

Enhancing your body’s NAD+ levels can significantly improve your health and vitality. Here are some practical tips on how to increase the coenzyme levels:


A regular physical activity is one of the most effective ways to boost NAD+ levels. Exercise stimulates the production of enzymes that help synthesize NAD+ and enhances its availability in the body. Aerobic exercises, in particular, can increase the expression of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme vital for the NAD+ salvage pathway. Furthermore, exercise induces the activation of sirtuins, a family of proteins that depend on NAD+ and are crucial for maintaining cellular health and metabolism.

Limiting Sun Exposure

While moderate exposure to sunlight benefits vitamin D synthesis, excessive UV radiation can deplete NAD+ levels. Ultraviolet light damages skin cells, which use significant amounts of NAD+ to repair DNA and regenerate damaged cells. Limiting sun exposure and protecting your skin can help preserve NAD+ levels, reducing the need for its consumption in cellular repair processes.

Heat Shock and Saunas

sauna area

Exposure to high temperatures, such as those experienced in a sauna, can also boost NAD+ levels. Heat shock proteins have been shown to increase the efficiency of the biochemical pathways that produce NAD+. Additionally, the heat from saunas induces a mild stress response similar to moderate exercise, which can promote longevity and health by increasing NAD+ production and activating sirtuins.

Dietary Changes

Incorporating specific nutrients into your diet can naturally boost NAD+ levels. Focus on foods high in NAD+, such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN). These are found in dairy products, fish like salmon, sardines, and mushrooms. Additionally, foods rich in polyphenols can enhance NAD+ production. These compounds help activate sirtuins, protein molecules that depend on NAD+ and are essential for cellular health. Reducing excessive caloric intake is also beneficial, as it can prevent the rapid depletion of NAD+ with high metabolic demand.

Fasting and Ketosis Diets

Intermittent fasting is shown to increase NAD+ levels. This involves cycling periods of eating with periods of fasting, which can range from 16 hours a day to two days a week, depending on the method. Fasting increases the activity of enzymes involved in the NAD+ salvage pathway, which recycles unused NAD+ back into active NAD+. A ketogenic diet also promotes higher NAD+ levels by mimicking the biological effects of fasting. When the body uses fat as a primary energy source, it produces ketone bodies and boosts NAD+, improving cellular metabolism and resilience.

NAD+ IV Therapy

NAD+ IV therapy is an efficient solution for those looking for an immediate increase in NAD+ levels. This therapy involves direct infusion of NAD+ into the bloodstream, ensuring that high levels of NAD+ reach the cells without being degraded. NAD+ IV therapy can quickly replenish cellular NAD+ levels, which is particularly beneficial for improving energy levels, accelerating recovery from physical exertion, enhancing mental clarity, and supporting overall cellular repair. Depending on individual health goals and conditions, regular sessions may be required to maintain optimal levels.

Boost Your NAD+ Levels with Treadwell’s NAD+ Therapy

Boost your NAD+ levels effectively with Treadwell’s specialized NAD+ IV drip therapy. At Treadwell, we understand the critical role that NAD+ plays in maintaining cellular health, energy metabolism, and overall vitality. We offer intramuscular (IM) injections and intravenous (IV) therapy options.

NAD+ IV Drip Therapy at Treadwell Houston

Our NAD+ IV Drip Therapy delivers the coenzyme directly into your bloodstream through an IV drip. This ensures maximum absorption and immediate availability to your body’s cells. NAD+ IV therapy is particularly effective for comprehensive rejuvenation, as it allows for higher dosages to be administered, which can rapidly replenish and boost NAD+ levels throughout the body. 

NAD+ IM Injections at Treadwell Houston

For those looking for a quicker and less invasive option, Treadwell also offers NAD+ through intramuscular injections. These injections provide faster administration than IV therapy and are an excellent alternative for efficiently boosting NAD+ levels. 

Both treatment options are designed to suit different lifestyle needs and personal preferences while providing the body with the benefits of increased NAD+ levels. Whether you choose the comprehensive approach of IV drip therapy or the convenience of IM injections, Treadwell’s treatments are tailored to effectively support your health and wellness goals.

At Treadwell, we aim to help you feel rejuvenated and vibrant, leveraging advanced therapies like NAD+ IV therapy and IM injections to optimize your health. Boosting your NAD+ levels can lead to numerous health benefits, including improved energy levels, enhanced mental clarity, faster recovery from physical exertion, better sleep and better overall cellular health. Choose Treadwell Houston for your NAD+ therapy and experience a new level of holistic wellness.

Nad IV therapy


Increasing your NAD+ levels can significantly impact your health, from boosting energy to slowing aging. These tips can enhance your NAD+ levels and improve your overall well-being.


Is NAD+ safe?

Yes, NAD+ is a naturally occurring substance in your body. Patients undergoing treatment for substance dependency have tolerated 1,000 mg administered daily for up to 10 days consecutively.

Why is IV NAD+ preferred over oral supplements?

At Treadwell, we provide high-dose NAD+ replenishment intravenously to ensure 100% absorption and bioavailability. This is unlike oral supplementation, where the dosage and absorption rate are significantly lower as the supplement must go through the digestion process and filter through the liver.

Do I need to fast before treatment?

However, we recommend you avoid foods high in fat or sugar before your infusion. We also recommend you avoid alcohol the day before and the day of your treatment to maximize the benefits and support cellular uptake.

Read more FAQs here.

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